Course detail

Biomechanics III - Cardiovascular

FSI-RBM Acad. year: 2026/2027 Winter semester

Learning outcomes of the course unit

Prerequisites

Planned learning activities and teaching methods

Assesment methods and criteria linked to learning outcomes

Language of instruction

Czech

Aims

Specification of controlled education, way of implementation and compensation for absences

The study programmes with the given course

Programme N-IMB-P: Engineering Mechanics and Biomechanics, Master's
branch BIO: Biomechanics, 6 credits, compulsory

Type of course unit

 

Lecture

26 hours, optionally

Syllabus

1. Introduction, contents of the course, mechanical properties of soft biological tissues and their experimental evaluation.
2. Fundamental medical information on cardiovascular system.
3. Mechanical properties of cells and their computational modelling.


4. Anatomy and physiology of myocardium.ECG, Starling's law, pressure-volume diagrams.


5. Anatomy, histology and physiology of blood vessels. Composition of blood vessel wall and its mechanical components. 


6. Arrangement of collagen fibres. Characteristics of flow in arteries, flow resistance.


7. Composition and rheological properties of blood, velocity profiles, Fahraeus-Lindqvist effect.
8. Theory of pulsatile flow, Moens-Korteweg equation, Womersley profiles.
9. Mechanical influence on atherosclerotic processes and principials of medical treatment. Arterial stents.
10. Vascular grafts (arterial replacements), types, properties, application, production.
11. Natural and artificial heart valves, principles of their function, overview of available products.
12. Ventricular assist devices and total artificial hearts.
13.Possibilities of computational modelling of cardiovascular system

Computer-assisted exercise

13 hours, compulsory

Syllabus

1.-2. FE model of animal cell.
3.-4. FE model of left ventricle. 
5.-6. FE model of aorta, residual stress.
7.-8. Evaluation of residual stress in arteral wall using volume growth (fictitious temperature) method. 
9.-10. Experiment – pulsatile flow in elastic tube.
11.-12.  FSI simulation of blood flow in arteries.
13. Course-unit credit.