Publication detail

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

LÍZAL, F. ELCNER, J. BĚLKA, M. JEDELSKÝ, J. HOPKE, P. ŠTARHA, P. DRUCKMÜLLEROVÁ, H. JÍCHA, M.

English title

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

Type

Peer-reviewed article not indexed in WoS or Scopus

Language

en

Original abstract

Deposition of fibers in human lungs is known as a health hazard. In-vitro measurements were performed with monodisperse glass fibers in a realistic model of human lungs up to seventh generation of branching to estimate the effect of fiber size and breathing pattern on fiber deposition. Deposited fibers were rinsed from the model segments and gathered on nitrocellulose filters. Phase-contrast microscopy with high resolution camera was used to capture images of filters with fibers. New software was developed for an automated image analysis and local deposition characteristics were calculated afterwards. The whole method proved to be a useful and valuable tool for the evaluation of fiber and particle deposition.

Keywords in English

Human Lungs, Deposition, Fibers, Image analysis

Released

2013-12-20

Publisher

Association for Engineering Mechanics

Location

Brno

ISSN

1802-1484

Journal

Engineering Mechanics

Volume

20

Number

3/4

Pages from–to

187–194

Pages count

8

BIBTEX


@article{BUT96300,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Philip K. {Hopke} and Pavel {Štarha} and Hana {Druckmüllerová} and Miroslav {Jícha}",
  title="Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis",
  journal="Engineering Mechanics",
  year="2013",
  volume="20",
  number="3/4",
  pages="187--194",
  issn="1802-1484"
}