Detail publikace

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

LÍZAL, F. ELCNER, J. BĚLKA, M. JEDELSKÝ, J. HOPKE, P. ŠTARHA, P. DRUCKMÜLLEROVÁ, H. JÍCHA, M.

Anglický název

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

Typ

Článek recenzovaný mimo WoS a Scopus

Jazyk

en

Originální abstrakt

Deposition of fibers in human lungs is known as a health hazard. In-vitro measurements were performed with monodisperse glass fibers in a realistic model of human lungs up to seventh generation of branching to estimate the effect of fiber size and breathing pattern on fiber deposition. Deposited fibers were rinsed from the model segments and gathered on nitrocellulose filters. Phase-contrast microscopy with high resolution camera was used to capture images of filters with fibers. New software was developed for an automated image analysis and local deposition characteristics were calculated afterwards. The whole method proved to be a useful and valuable tool for the evaluation of fiber and particle deposition.

Klíčová slova anglicky

Human Lungs, Deposition, Fibers, Image analysis

Vydáno

2013-12-20

Nakladatel

Association for Engineering Mechanics

Místo

Brno

ISSN

1802-1484

Časopis

Engineering Mechanics

Ročník

20

Číslo

3/4

Strany od–do

187–194

Počet stran

8

BIBTEX


@article{BUT96300,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Philip K. {Hopke} and Pavel {Štarha} and Hana {Druckmüllerová} and Miroslav {Jícha}",
  title="Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis",
  journal="Engineering Mechanics",
  year="2013",
  volume="20",
  number="3/4",
  pages="187--194",
  issn="1802-1484"
}