Detail publikace

Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels

David Nečas, Daniel Němeček, Jan Gregora, David Rebenda, Zuzana Kadlecová, Ivana Chamradová, Monika Trudičová, Pavel Čípek, Petr Čípek, Ladislav Šnajdárek, Lucy Vojtová, Martin Vrbka, Ivan Křupka, Martin Hartl

Anglický název

Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels

Typ

Článek WoS

Jazyk

en

Originální abstrakt

This study compares the biotribological and structural behavior of PVA and pHEMA hydrogels under conditions simulating the cartilage environment to understand the lubrication mechanisms. PVA samples exhibited very low apparent friction coefficients and high-water uptake due to their hydrophilic, hydroxyl-rich network. In contrast, pHEMA hydrogels showed higher friction but substantially enhanced wear resistance, particularly under extended sliding against rough counterfaces. While PVA offers excellent lubrication performance, its wear stability remains limited. On the other hand, the low wear observed in pHEMA-despite its higher friction-suggests strong structural resilience, making it a promising platform for further tailoring toward cartilage-mimicking applications. The results highlight the importance of balancing interfacial lubrication and mechanical durability when designing hydrogel-based cartilage replacements.

Klíčová slova anglicky

Absorption; Friction; Hydrogels; Lubrication; Wear

Vydáno

2025-12-08

Nakladatel

American Chemical Society

Ročník

10

Číslo

51

Strany od–do

63441–63454

Počet stran

14

BIBTEX


@article{BUT200519,
  author="David {Nečas} and Daniel {Němeček} and Jan {Gregora} and David {Rebenda} and Zuzana {Kadlecová} and Ivana {Chamradová} and Monika {Trudičová} and Pavel {Čípek} and Petr {Čípek} and Ladislav {Šnajdárek} and Lucy {Vojtová} and Martin {Vrbka} and Ivan {Křupka} and Martin {Hartl}",
  title="Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels",
  journal="ACS Omega",
  year="2025",
  volume="10",
  number="51",
  pages="63441--63454",
  doi="10.1021/acsomega.5c10283",
  issn="2470-1343",
  url="https://pubs.acs.org/doi/10.1021/acsomega.5c10283"
}