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[nazev] => MECHANICAL PROPERTIES OF DIFFERENT TISSUES OF CAROTID ATHEROMA: EXPERIMENTAL APPROACH
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[popis] => Atherosclerosis is a life-threatening disease mainly occurring in carotid or coronary arteries. In case of carotid arteries, the rupture of fibrous cap encapsuling the cell debris, also known as lipid core, can induce a stroke. In clinics, the severity of the plaque is assessed only through the size of the stenosis. Computational modelling can help in the decision-making process and can bring deeper insight into the dilemma. The tissues both above the lipid core (referred to as fibrous cap) and beneath it are often not distinguished and specified as “fibrous tissue”. Although some publications suggested that both these tissues have similar mechanical properties [1], others recommend that plaque specific material properties are needed [2]. In this study, the potential difference in mechanical response between fibrous cap and original artery wall (media) is investigated combining histological and mechanical experiments.
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[klicova_slova] => atherosclerosis; carotid atheroma; experiment
[klicova_slova_orig] => atherosclerosis; carotid atheroma; experiment
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author="Anna {Hrubanová} and Zdeněk {Bednařík} and Luboš {Kubíček} and Jiří {Burša}",
title="MECHANICAL PROPERTIES OF DIFFERENT TISSUES OF CAROTID ATHEROMA: EXPERIMENTAL APPROACH",
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year="2023",
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[popis_en] => Atherosclerosis is a life-threatening disease mainly occurring in carotid or coronary arteries. In case of carotid arteries, the rupture of fibrous cap encapsuling the cell debris, also known as lipid core, can induce a stroke. In clinics, the severity of the plaque is assessed only through the size of the stenosis. Computational modelling can help in the decision-making process and can bring deeper insight into the dilemma. The tissues both above the lipid core (referred to as fibrous cap) and beneath it are often not distinguished and specified as “fibrous tissue”. Although some publications suggested that both these tissues have similar mechanical properties [1], others recommend that plaque specific material properties are needed [2]. In this study, the potential difference in mechanical response between fibrous cap and original artery wall (media) is investigated combining histological and mechanical experiments.
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[nazev_orig] => IN SILICO HEMODYNAMICAL SIMULATIONS SHOW SECONDARY BENEFITS OF ANTIHYPERTENSIVE DRUGS
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[popis] => Although preventable, hypertension and hypertensive renal disease remain one of the major global risk factors for cardiovascular diseases, especially in the developed world [1]. Hypertension is defined as a chronically increased blood pressure (BP) above 140/90 mmHg and is related to an increase in peripheral resistance and decrease in arterial distensibility [2], similarly to an aging [1]. Available evidence confirms the ability of all five basic groups of antihypertensives to decrease arterial stiffness and consequently the BP in the long-term application [3]. Although proper treatment of hypertension attenuates its influence, the mechanisms by which hypertension accelerates atherosclerosis are poorly understood [4]. It is known that flow waveform for older subjects differs substantially from the young one mainly due to elevated arterial stiffness and consequently early wave reflection [5]. Moreover, the decreasing arterial stiffness via proper treatment of hypertension shifts the shape of the flow waveform to a young and healthy one [6]. Since arterial stiffness can be lowered through long-term application of antihypertensives, benefits of medical therapy could be not only in lowering the BP and peripheral resistance but also in improving the hemodynamic conditions.
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[klicova_slova] => HEMODYNAMICAL SIMULATIONS; ANTIHYPERTENSIVE DRUGS
[klicova_slova_orig] => HEMODYNAMICAL SIMULATIONS; ANTIHYPERTENSIVE DRUGS
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author="Jiří {Jagoš} and Jiří {Kohút} and Tomáš {Novotný} and Tomáš {Křivka} and Petr {Hájek} and Martin {Formánek} and Jiří {Burša}",
title="IN SILICO HEMODYNAMICAL SIMULATIONS SHOW SECONDARY BENEFITS OF ANTIHYPERTENSIVE DRUGS",
booktitle="ESB 2023 BOOK OF ABSTRACTS",
year="2023",
number="28",
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[popis_en] => Although preventable, hypertension and hypertensive renal disease remain one of the major global risk factors for cardiovascular diseases, especially in the developed world [1]. Hypertension is defined as a chronically increased blood pressure (BP) above 140/90 mmHg and is related to an increase in peripheral resistance and decrease in arterial distensibility [2], similarly to an aging [1]. Available evidence confirms the ability of all five basic groups of antihypertensives to decrease arterial stiffness and consequently the BP in the long-term application [3]. Although proper treatment of hypertension attenuates its influence, the mechanisms by which hypertension accelerates atherosclerosis are poorly understood [4]. It is known that flow waveform for older subjects differs substantially from the young one mainly due to elevated arterial stiffness and consequently early wave reflection [5]. Moreover, the decreasing arterial stiffness via proper treatment of hypertension shifts the shape of the flow waveform to a young and healthy one [6]. Since arterial stiffness can be lowered through long-term application of antihypertensives, benefits of medical therapy could be not only in lowering the BP and peripheral resistance but also in improving the hemodynamic conditions.
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[nazev] => VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP
[nazev_orig] => VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP
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[popis] => In clinical practice, roller pumps (RPs) are mostly used in two medical methods – veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardio-pulmonary bypass (CPB). Currently, centrifugal pumps (CPs) stand the competition in the VA-ECMO, mainly due to the shorter lifespan of peristaltic tubing [1]. However, the hemolysis-related complications (e.g., hemolytic anemia, hyperbilirubinemia, and acute renal failure) are usually much more prominent in CPs [2][3]. Main difference between CP and RP is that the former provides continuous flow due to the inherent design of the pump while the latter produces pulsatile flow. The pulsatile flow has been attributed to several benefits such as shorter need of intensive care, better microcirculation, lower inflammatory events, and better perfusion to organs [4]. Moreover, the correct synchronization between pulsatile flow and ECG may support the heart performance during VA-ECMO session [5].
Even though the study [5] demonstrated the pulsatile feasibility of CPs (achieved by varying the rotational speed), it carries certain limitations (e.g., the pulsatile effect diminishes with higher flow rates and may increase hemolysis). On the other hand, RPs generate intrinsically pulsatile flow, and the pressure and flow waveforms can be widely modulated through varying rotational speed profile (RSP) [6].
Since hemolysis is a crucial factor in clinical practice, the paper focuses on its evaluation within an in-house developed two-roller pump with full occlusion using computational simulations with experimentally obtained boundary conditions.
[popis_orig] => In clinical practice, roller pumps (RPs) are mostly used in two medical methods – veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardio-pulmonary bypass (CPB). Currently, centrifugal pumps (CPs) stand the competition in the VA-ECMO, mainly due to the shorter lifespan of peristaltic tubing [1]. However, the hemolysis-related complications (e.g., hemolytic anemia, hyperbilirubinemia, and acute renal failure) are usually much more prominent in CPs [2][3]. Main difference between CP and RP is that the former provides continuous flow due to the inherent design of the pump while the latter produces pulsatile flow. The pulsatile flow has been attributed to several benefits such as shorter need of intensive care, better microcirculation, lower inflammatory events, and better perfusion to organs [4]. Moreover, the correct synchronization between pulsatile flow and ECG may support the heart performance during VA-ECMO session [5].
Even though the study [5] demonstrated the pulsatile feasibility of CPs (achieved by varying the rotational speed), it carries certain limitations (e.g., the pulsatile effect diminishes with higher flow rates and may increase hemolysis). On the other hand, RPs generate intrinsically pulsatile flow, and the pressure and flow waveforms can be widely modulated through varying rotational speed profile (RSP) [6].
Since hemolysis is a crucial factor in clinical practice, the paper focuses on its evaluation within an in-house developed two-roller pump with full occlusion using computational simulations with experimentally obtained boundary conditions.
[klicova_slova] => ROLLER PUMP; HEMOLYSIS
[klicova_slova_orig] => ROLLER PUMP; HEMOLYSIS
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[citace_text] => KOHÚT, J.; JAGOŠ, J.; FORMÁNEK, M.; BURŠA, J. VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP. ESB 2023 BOOK OF ABSTRACTS. Maastricht: 2023. 1 p.
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author="Jiří {Kohút} and Jiří {Jagoš} and Martin {Formánek} and Jiří {Burša}",
title="VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP",
booktitle="ESB 2023 BOOK OF ABSTRACTS",
year="2023",
number="28",
pages="1",
address="Maastricht",
url="https://esbiomech.org/conference/wp-content/uploads/2023/ESB2023_Book_of_Abstracts.pdf"
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[oecd_tree_oblast_nazev] => 1. Natural Sciences
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[oecd_tree_obor_nazev] => 1.6 Biological sciences
[oecd_tree_podobor_id] => 10610
[oecd_tree_podobor_nazev] => Biophysics
[poznamka_metriky] =>
[nazev_en] => VARIABLE ROTATIONAL SPEED SUBSTANTIALLY REDUCE THE RATE OF HEMOLYSIS WITHIN IN-HOUSE ROLLER PUMP
[popis_en] => In clinical practice, roller pumps (RPs) are mostly used in two medical methods – veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardio-pulmonary bypass (CPB). Currently, centrifugal pumps (CPs) stand the competition in the VA-ECMO, mainly due to the shorter lifespan of peristaltic tubing [1]. However, the hemolysis-related complications (e.g., hemolytic anemia, hyperbilirubinemia, and acute renal failure) are usually much more prominent in CPs [2][3]. Main difference between CP and RP is that the former provides continuous flow due to the inherent design of the pump while the latter produces pulsatile flow. The pulsatile flow has been attributed to several benefits such as shorter need of intensive care, better microcirculation, lower inflammatory events, and better perfusion to organs [4]. Moreover, the correct synchronization between pulsatile flow and ECG may support the heart performance during VA-ECMO session [5].
Even though the study [5] demonstrated the pulsatile feasibility of CPs (achieved by varying the rotational speed), it carries certain limitations (e.g., the pulsatile effect diminishes with higher flow rates and may increase hemolysis). On the other hand, RPs generate intrinsically pulsatile flow, and the pressure and flow waveforms can be widely modulated through varying rotational speed profile (RSP) [6].
Since hemolysis is a crucial factor in clinical practice, the paper focuses on its evaluation within an in-house developed two-roller pump with full occlusion using computational simulations with experimentally obtained boundary conditions.
[klicova_slova_en] => ROLLER PUMP; HEMOLYSIS
[vysledek_datum] => 2023-07-09T00:00:00+02:00
)
[3] => Array
(
[vysledek_id] => 184929
[vysledek_druh_id] => CONPAX
[ex_vysledek_id] => 149192
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[nazev] => CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION
[nazev_orig] => CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION
[duvernost_udaju_id] => S
[popis] => Cellular mechanics undergo complex changes during cancer progression in parallel with metabolic reprogramming due to altered demands on its motility. As the cytoskeleton forms a major part of cellular stiffness, this study focuses mainly on exploring cytoskeletal changes in cancer cells and evaluating their direct impact on cellular stiffness. However, the association between cellular stiffness and tumor cell aggressiveness is not straightforward and results vary depending on tumor type. The main aim of this study was to explore the relationship between the altered inner structural arrangement and cell aggressivity in prostate cancer cells using a combination of laboratory and computational methods.
[popis_orig] => Cellular mechanics undergo complex changes during cancer progression in parallel with metabolic reprogramming due to altered demands on its motility. As the cytoskeleton forms a major part of cellular stiffness, this study focuses mainly on exploring cytoskeletal changes in cancer cells and evaluating their direct impact on cellular stiffness. However, the association between cellular stiffness and tumor cell aggressiveness is not straightforward and results vary depending on tumor type. The main aim of this study was to explore the relationship between the altered inner structural arrangement and cell aggressivity in prostate cancer cells using a combination of laboratory and computational methods.
[klicova_slova] => CELLULAR STIFFNESS; CANCER-INDUCED CYTOSKELETON; CELLULAR MECHANICS
[klicova_slova_orig] => CELLULAR STIFFNESS; CANCER-INDUCED CYTOSKELETON; CELLULAR MECHANICS
[url] => https://esbiomech.org/conference/wp-content/uploads/2023/ESB2023_Book_of_Abstracts.pdf
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[vycet_osob] => JADRNÁ, L.; GUMULEC, J.; BURŠA, J.
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[kategorie_nazev] => Publikační výsledky
[druh_nazev] => Stať ve sborníku mimo WoS a Scopus
[druh_popis] => Stať ve sborníku mimo WoS a Scopus
[stav] => Schválený
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[upravil] => Informační systém Automat
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[upd_ts] => 2025-09-22
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[citace_text] => JADRNÁ, L.; GUMULEC, J.; BURŠA, J. CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION. ESB 2023 BOOK OF ABSTRACTS. Maastricht: ESB, 2023. 1 p.
[citace_html] => JADRNÁ, L.; GUMULEC, J.; BURŠA, J. CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION. ESB 2023 BOOK OF ABSTRACTS. Maastricht: ESB, 2023. 1 p.
[citace_rtf] =>
[citace_bibtex] => @inproceedings{BUT184929,
author="Lucie {Jadrná} and Jaromír {Gumulec} and Jiří {Burša}",
title="CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION",
booktitle="ESB 2023 BOOK OF ABSTRACTS",
year="2023",
number="28",
pages="1",
publisher="ESB",
address="Maastricht",
url="https://esbiomech.org/conference/wp-content/uploads/2023/ESB2023_Book_of_Abstracts.pdf"
}
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[nazev_en] => CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION
[popis_en] => Cellular mechanics undergo complex changes during cancer progression in parallel with metabolic reprogramming due to altered demands on its motility. As the cytoskeleton forms a major part of cellular stiffness, this study focuses mainly on exploring cytoskeletal changes in cancer cells and evaluating their direct impact on cellular stiffness. However, the association between cellular stiffness and tumor cell aggressiveness is not straightforward and results vary depending on tumor type. The main aim of this study was to explore the relationship between the altered inner structural arrangement and cell aggressivity in prostate cancer cells using a combination of laboratory and computational methods.
[klicova_slova_en] => CELLULAR STIFFNESS; CANCER-INDUCED CYTOSKELETON; CELLULAR MECHANICS
[vysledek_datum] => 2023-07-09T00:00:00+02:00
)
[4] => Array
(
[vysledek_id] => 185055
[vysledek_druh_id] => ARTWOS
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[nazev] => Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy
[nazev_orig] => Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy
[duvernost_udaju_id] => S
[popis] => In this study, microstructural features direct metal laser melted (DMLM) aluminium–siliconmagnesium
(AlSi10Mg) are investigated using advanced transmission electron microscopy (TEM) and high-resolution TEM (HRTEM). The focus is on post-processing by ECAP (Equal Channel Angular Pressing) and its effects on grain refinement, stacking fault formation and dislocation accumulation. In addition, the strength enhancing role of stacking faults is for the first time quantified. The results show that ECAP can increase the yield strength from 294 to 396 MPa, while the elongation increases from 2.4% to 6%. These results show that ECAP processing offers a new approach for producing AlSi10Mg products with improved strength and ductility.
[popis_orig] => In this study, microstructural features direct metal laser melted (DMLM) aluminium–siliconmagnesium
(AlSi10Mg) are investigated using advanced transmission electron microscopy (TEM) and high-resolution TEM (HRTEM). The focus is on post-processing by ECAP (Equal Channel Angular Pressing) and its effects on grain refinement, stacking fault formation and dislocation accumulation. In addition, the strength enhancing role of stacking faults is for the first time quantified. The results show that ECAP can increase the yield strength from 294 to 396 MPa, while the elongation increases from 2.4% to 6%. These results show that ECAP processing offers a new approach for producing AlSi10Mg products with improved strength and ductility.
[klicova_slova] => Equal Channel Angular Pressing;grain refinement;stacking fault; dislocation accumulation;transmission electron microscopy
[klicova_slova_orig] => Equal Channel Angular Pressing;grain refinement;stacking fault; dislocation accumulation;transmission electron microscopy
[url] => https://www.nature.com/articles/s41598-023-43448-5
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[originalni_jazyk] => en
[schvalil_id] => 1770
[schvaleno] => 2024-03-05
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[slozka_id] => 138136
[posledni_diagnostika] =>
[vycet_osob] => SNOPIŃSKI, P.; KOTOUL, M.; PETRUŠKA, J.; RUSZ, S.; ŻABA, K.; HILŠER, O.
[pocet_tvurcu] => 6
[tvurci_ids] =>
[poznamka] =>
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[kod_doi] => 10.1038/s41598-023-43448-5
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[stav] => Schválený
[vysledek_kategorie_id] => PV
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[citace_text] => SNOPIŃSKI, P.; KOTOUL, M.; PETRUŠKA, J.; RUSZ, S.; ŻABA, K.; HILŠER, O. Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy. Scientific Reports, 2023, vol. 13, no. 1, p. 1-16. ISSN: 2045-2322.
[citace_html] => SNOPIŃSKI, P.; KOTOUL, M.; PETRUŠKA, J.; RUSZ, S.; ŻABA, K.; HILŠER, O. Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy. Scientific Reports, 2023, vol. 13, no. 1, p. 1-16. ISSN: 2045-2322.
[citace_rtf] =>
[citace_bibtex] => @article{BUT185055,
author="Przemysław {Snopiński} and Michal {Kotoul} and Jindřich {Petruška} and Stanislav {Rusz} and Krzysztof {Żaba} and Ondřej {Hilšer}",
title="Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy",
journal="Scientific Reports",
year="2023",
volume="13",
number="1",
pages="1--16",
doi="10.1038/s41598-023-43448-5",
issn="2045-2322",
url="https://www.nature.com/articles/s41598-023-43448-5"
}
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[oecd_tree_podobor_nazev] => Materials engineering
[poznamka_metriky] =>
[nazev_en] => Revealing the strengthening contribution of stacking faults, dislocations and grain boundaries in severely deformed LPBF AlSi10Mg alloy
[popis_en] => In this study, microstructural features direct metal laser melted (DMLM) aluminium–siliconmagnesium
(AlSi10Mg) are investigated using advanced transmission electron microscopy (TEM) and high-resolution TEM (HRTEM). The focus is on post-processing by ECAP (Equal Channel Angular Pressing) and its effects on grain refinement, stacking fault formation and dislocation accumulation. In addition, the strength enhancing role of stacking faults is for the first time quantified. The results show that ECAP can increase the yield strength from 294 to 396 MPa, while the elongation increases from 2.4% to 6%. These results show that ECAP processing offers a new approach for producing AlSi10Mg products with improved strength and ductility.
[klicova_slova_en] => Equal Channel Angular Pressing;grain refinement;stacking fault; dislocation accumulation;transmission electron microscopy
[vysledek_datum] => 2023-09-27T00:00:00+02:00
)
[5] => Array
(
[vysledek_id] => 185584
[vysledek_druh_id] => ARTWOS
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[nazev] => Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components
[nazev_orig] => Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components
[duvernost_udaju_id] => S
[popis] => Numerous studies have compared metal-backed components (MBTs) and all-polyethylene tibial components (APTs), but none of them specifically analysed the clinical results and the overall patient preference in patients who had undergone a staged bilateral knee replacement. The purpose of this study is to compare clinical results, perceived range of motion, and overall implant preference among patients who had undergone staged bilateral knee replacement with an APT and contralateral knee replacement with MBTs. A dataset of 62 patients from a single centre who underwent staged bilateral TKA between 2009 and 2022 was selected and retrospectively analysed. Tibial component removal was performed in three knees overall, all of which had MBTs. The mean measured Knee Score (KS) of knees with APTs was 78.37 and that of contralateral knees with MBTs was 77.4. The mean measured Function (FS) of knees with APTs was 78.22, and that of contralateral knees with MBs was 76.29. The mean flexion angle of knees with APTs was 103.8 and that for knees with MBTs was 101.04 degrees. A total of 54.8% of the patients preferred the knee that received APTs over contralateral MBTs. In our cohort, TKA with an APT in one knee and an MBT in the contralateral knee recorded similar clinical results and perceived ranges of motion. Patients in general preferred the knee that received an APT over contralateral knee with an MBT.
[popis_orig] => Numerous studies have compared metal-backed components (MBTs) and all-polyethylene tibial components (APTs), but none of them specifically analysed the clinical results and the overall patient preference in patients who had undergone a staged bilateral knee replacement. The purpose of this study is to compare clinical results, perceived range of motion, and overall implant preference among patients who had undergone staged bilateral knee replacement with an APT and contralateral knee replacement with MBTs. A dataset of 62 patients from a single centre who underwent staged bilateral TKA between 2009 and 2022 was selected and retrospectively analysed. Tibial component removal was performed in three knees overall, all of which had MBTs. The mean measured Knee Score (KS) of knees with APTs was 78.37 and that of contralateral knees with MBTs was 77.4. The mean measured Function (FS) of knees with APTs was 78.22, and that of contralateral knees with MBs was 76.29. The mean flexion angle of knees with APTs was 103.8 and that for knees with MBTs was 101.04 degrees. A total of 54.8% of the patients preferred the knee that received APTs over contralateral MBTs. In our cohort, TKA with an APT in one knee and an MBT in the contralateral knee recorded similar clinical results and perceived ranges of motion. Patients in general preferred the knee that received an APT over contralateral knee with an MBT.
[klicova_slova] => bilateral knee replacement; total knee arthroplasty; all-polyethylene tibia; metal-backed
tibia; staged bilateral knee arthroplasty
[klicova_slova_orig] => bilateral knee replacement; total knee arthroplasty; all-polyethylene tibia; metal-backed
tibia; staged bilateral knee arthroplasty
[url] => https://www.mdpi.com/2077-0383/12/23/7438
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[originalni_jazyk] => en
[schvalil_id] => 51108
[schvaleno] => 2024-02-22
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[slozka_id] => 141820
[posledni_diagnostika] =>
[vycet_osob] => NACHTNEBL, L.; APOSTOLOPOULOS, V.; MAHDAL, M.; PAZOUREK, L.; BRANČÍK, P.; VALOUŠEK, T.; BOHÁČ, P.; TOMÁŠ, T.
[pocet_tvurcu] => 8
[tvurci_ids] =>
[poznamka] =>
[typ_nazev] =>
[kod_doi] => 10.3390/jcm12237438
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[pocet_zaznamu] =>
[zverejneno] => 1
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[korespondencni_autor] =>
[posledni_autor] =>
[znamka] =>
[kategorie_nazev] => Publikační výsledky
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[druh_popis] => Článek v odborném periodiku je obsažen v databázi Web of Science společností Thomson Reuters s příznakem „Article“, „Review“ nebo „Letter“
[stav] => Schválený
[vysledek_kategorie_id] => PV
[vysledek_system_kategorie_id] => PU
[vysledek_stav_id] => 3
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[upravil] => Informační systém Automat
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[ins_ts] => 2025-09-22
[upd_ts] => 2025-09-22
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[identifikator_popis] =>
[riv_dodavka_id] => 3367
[riv_dodavka_oznaceni] => RIV24-MSM-26210___
[riv_dodavka_rok] => 2024
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[citace_text] => NACHTNEBL, L.; APOSTOLOPOULOS, V.; MAHDAL, M.; PAZOUREK, L.; BRANČÍK, P.; VALOUŠEK, T.; BOHÁČ, P.; TOMÁŠ, T. Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components. Journal of Clinical Medicine, 2023, vol. 12, no. 23, p. 1-9. ISSN: 2077-0383.
[citace_html] => NACHTNEBL, L.; APOSTOLOPOULOS, V.; MAHDAL, M.; PAZOUREK, L.; BRANČÍK, P.; VALOUŠEK, T.; BOHÁČ, P.; TOMÁŠ, T. Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components. Journal of Clinical Medicine, 2023, vol. 12, no. 23, p. 1-9. ISSN: 2077-0383.
[citace_rtf] =>
[citace_bibtex] => @article{BUT185584,
author="Luboš {Nachtnebl} and Vasileios {Apostolopoulos} and Michal {Mahdal} and Lukáš {Pazourek} and Pavel {Brančík} and Tomáš {Valoušek} and Petr {Boháč} and Tomáš {Tomáš}",
title="Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components",
journal="Journal of Clinical Medicine",
year="2023",
volume="12",
number="23",
pages="1--9",
doi="10.3390/jcm12237438",
url="https://www.mdpi.com/2077-0383/12/23/7438"
}
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[nazev_en] => Implant Preference and Clinical Outcomes of Patients with Staged Bilateral Total Knee Arthroplasty: All-Polyethylene and Contralateral Metal-Backed Tibial Components
[popis_en] => Numerous studies have compared metal-backed components (MBTs) and all-polyethylene tibial components (APTs), but none of them specifically analysed the clinical results and the overall patient preference in patients who had undergone a staged bilateral knee replacement. The purpose of this study is to compare clinical results, perceived range of motion, and overall implant preference among patients who had undergone staged bilateral knee replacement with an APT and contralateral knee replacement with MBTs. A dataset of 62 patients from a single centre who underwent staged bilateral TKA between 2009 and 2022 was selected and retrospectively analysed. Tibial component removal was performed in three knees overall, all of which had MBTs. The mean measured Knee Score (KS) of knees with APTs was 78.37 and that of contralateral knees with MBTs was 77.4. The mean measured Function (FS) of knees with APTs was 78.22, and that of contralateral knees with MBs was 76.29. The mean flexion angle of knees with APTs was 103.8 and that for knees with MBTs was 101.04 degrees. A total of 54.8% of the patients preferred the knee that received APTs over contralateral MBTs. In our cohort, TKA with an APT in one knee and an MBT in the contralateral knee recorded similar clinical results and perceived ranges of motion. Patients in general preferred the knee that received an APT over contralateral knee with an MBT.
[klicova_slova_en] => bilateral knee replacement; total knee arthroplasty; all-polyethylene tibia; metal-backed
tibia; staged bilateral knee arthroplasty
[vysledek_datum] => 2023-11-30T00:00:00+01:00
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[popis] => Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where two collagen fibre families are seldom found. Moreover, bimodal distributions of fibre directions may originate also from their waviness combined with ignoring differences between local and global fibre orientations. In contrast, if the model parameters are identified without histological information on collagen fibre directions, the resulting mean angles of both fibre families are close to +/- 45 degrees, which contradicts nearly all histologic findings. The presented study exploited automated polarized light microscopy for detection of collagen fibre directions in porcine aorta under different biaxial extensions and approximated the resulting histograms with unimodal and bimodal von Mises distributions. Their comparison showed dominantly circumferential orientation of collagen fibres. Their concentration parameter for unimodal distributions increased with circumferential load, no matter if acting uniaxially or equibiaxially. For bimodal distributions, the angle between both dominant fibre directions (chosen as measure of fibre alignment) decreased similarly for both uniaxial and equibiaxial loads. These results indicate the existence of a single family of wavy circumferential collagen fibres in all layers of the aortic wall. Bimodal distributions of fibre directions presented sometimes in literature may come rather from waviness of circumferentially arranged fibres than from two symmetric families of helical fibres. To obtain a final evidence, the fibre orientation should be analysed together with their waviness.
[popis_orig] => Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where two collagen fibre families are seldom found. Moreover, bimodal distributions of fibre directions may originate also from their waviness combined with ignoring differences between local and global fibre orientations. In contrast, if the model parameters are identified without histological information on collagen fibre directions, the resulting mean angles of both fibre families are close to +/- 45 degrees, which contradicts nearly all histologic findings. The presented study exploited automated polarized light microscopy for detection of collagen fibre directions in porcine aorta under different biaxial extensions and approximated the resulting histograms with unimodal and bimodal von Mises distributions. Their comparison showed dominantly circumferential orientation of collagen fibres. Their concentration parameter for unimodal distributions increased with circumferential load, no matter if acting uniaxially or equibiaxially. For bimodal distributions, the angle between both dominant fibre directions (chosen as measure of fibre alignment) decreased similarly for both uniaxial and equibiaxial loads. These results indicate the existence of a single family of wavy circumferential collagen fibres in all layers of the aortic wall. Bimodal distributions of fibre directions presented sometimes in literature may come rather from waviness of circumferentially arranged fibres than from two symmetric families of helical fibres. To obtain a final evidence, the fibre orientation should be analysed together with their waviness.
[klicova_slova] => Arterial wall; Collagen; Fibre direction; Fibre waviness; Concentration parameter
[klicova_slova_orig] => Arterial wall; Collagen; Fibre direction; Fibre waviness; Concentration parameter
[url] => https://www.sciencedirect.com/science/article/pii/S0021929023004396
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[citace_text] => TURČANOVÁ, M.; FISCHER, J.; HERMANOVÁ, M.; BEDNAŘÍK, Z.; SKÁCEL, P.; BURŠA, J. Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres. JOURNAL OF BIOMECHANICS, 2023, vol. 161, no. 12, p. 1-8. ISSN: 0021-9290.
[citace_html] => TURČANOVÁ, M.; FISCHER, J.; HERMANOVÁ, M.; BEDNAŘÍK, Z.; SKÁCEL, P.; BURŠA, J. Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres. JOURNAL OF BIOMECHANICS, 2023, vol. 161, no. 12, p. 1-8. ISSN: 0021-9290.
[citace_rtf] =>
[citace_bibtex] => @article{BUT186748,
author="Michaela {Turčanová} and Jiří {Fischer} and Markéta {Hermanová} and Zdeněk {Bednařík} and Pavel {Skácel} and Jiří {Burša}",
title="Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres",
journal="JOURNAL OF BIOMECHANICS",
year="2023",
volume="161",
number="12",
pages="1--8",
doi="10.1016/j.jbiomech.2023.111868",
issn="0021-9290",
url="https://www.sciencedirect.com/science/article/pii/S0021929023004396"
}
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[nazev_en] => Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres
[popis_en] => Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where two collagen fibre families are seldom found. Moreover, bimodal distributions of fibre directions may originate also from their waviness combined with ignoring differences between local and global fibre orientations. In contrast, if the model parameters are identified without histological information on collagen fibre directions, the resulting mean angles of both fibre families are close to +/- 45 degrees, which contradicts nearly all histologic findings. The presented study exploited automated polarized light microscopy for detection of collagen fibre directions in porcine aorta under different biaxial extensions and approximated the resulting histograms with unimodal and bimodal von Mises distributions. Their comparison showed dominantly circumferential orientation of collagen fibres. Their concentration parameter for unimodal distributions increased with circumferential load, no matter if acting uniaxially or equibiaxially. For bimodal distributions, the angle between both dominant fibre directions (chosen as measure of fibre alignment) decreased similarly for both uniaxial and equibiaxial loads. These results indicate the existence of a single family of wavy circumferential collagen fibres in all layers of the aortic wall. Bimodal distributions of fibre directions presented sometimes in literature may come rather from waviness of circumferentially arranged fibres than from two symmetric families of helical fibres. To obtain a final evidence, the fibre orientation should be analysed together with their waviness.
[klicova_slova_en] => Arterial wall; Collagen; Fibre direction; Fibre waviness; Concentration parameter
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[nazev] => Need for transverse strain data for fitting constitutive models of arterial tissue to uniaxial tests
[nazev_orig] => Need for transverse strain data for fitting constitutive models of arterial tissue to uniaxial tests
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[popis] => The study deals with the process of estimation of material parameters from uniaxial test data of arterial tissue and focuses on the role of transverse strains. Two fitting strategies are analyzed and their impact on the predictive and descriptive capabilities of the resulting model is evaluated. The standard fitting procedure (strategy A) based on longitudinal stress-strain curves is compared with the enhanced approach (strategy B) taking also the transverse strain test data into account. The study is performed on a large set of material data adopted from literature and for a variety of constitutive models developed for fibrous soft tissues. The standard procedure (A) ignoring the transverse strain test data is found rather hazardous, leading often to unrealistic predictions of the model exhibiting auxetic behaviour. In contrast, the alternative fitting method (B) ensures a realistic strain response of the model and is proved to be superior since it does not require any significant demands of computational effort or additional testing. The results presented in this paper show that even the artificial transverse strain data (i.e., not measured during testing but generated ex post, based on assumed Poisson’s ratio) are much less hazardous than total disregard of the transverse strain response.
[popis_orig] => The study deals with the process of estimation of material parameters from uniaxial test data of arterial tissue and focuses on the role of transverse strains. Two fitting strategies are analyzed and their impact on the predictive and descriptive capabilities of the resulting model is evaluated. The standard fitting procedure (strategy A) based on longitudinal stress-strain curves is compared with the enhanced approach (strategy B) taking also the transverse strain test data into account. The study is performed on a large set of material data adopted from literature and for a variety of constitutive models developed for fibrous soft tissues. The standard procedure (A) ignoring the transverse strain test data is found rather hazardous, leading often to unrealistic predictions of the model exhibiting auxetic behaviour. In contrast, the alternative fitting method (B) ensures a realistic strain response of the model and is proved to be superior since it does not require any significant demands of computational effort or additional testing. The results presented in this paper show that even the artificial transverse strain data (i.e., not measured during testing but generated ex post, based on assumed Poisson’s ratio) are much less hazardous than total disregard of the transverse strain response.
[klicova_slova] => Arterial wall mechanics; Constitutive models; Transverse deformation; Poisson's ratio; Model calibration; Hyperfit software
[klicova_slova_orig] => Arterial wall mechanics; Constitutive models; Transverse deformation; Poisson's ratio; Model calibration; Hyperfit software
[url] => https://www.sciencedirect.com/science/article/pii/S1751616123005477
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[citace_text] => SKÁCEL, P.; BURŠA, J. Need for transverse strain data for fitting constitutive models of arterial tissue to uniaxial tests. Journal of the Mechanical Behavior of Biomedical Materials, 2024, vol. 150, no. 150, p. 106194-1 (106194-14 p.)ISSN: 1751-6161.
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[nazev_en] => Need for transverse strain data for fitting constitutive models of arterial tissue to uniaxial tests
[popis_en] => The study deals with the process of estimation of material parameters from uniaxial test data of arterial tissue and focuses on the role of transverse strains. Two fitting strategies are analyzed and their impact on the predictive and descriptive capabilities of the resulting model is evaluated. The standard fitting procedure (strategy A) based on longitudinal stress-strain curves is compared with the enhanced approach (strategy B) taking also the transverse strain test data into account. The study is performed on a large set of material data adopted from literature and for a variety of constitutive models developed for fibrous soft tissues. The standard procedure (A) ignoring the transverse strain test data is found rather hazardous, leading often to unrealistic predictions of the model exhibiting auxetic behaviour. In contrast, the alternative fitting method (B) ensures a realistic strain response of the model and is proved to be superior since it does not require any significant demands of computational effort or additional testing. The results presented in this paper show that even the artificial transverse strain data (i.e., not measured during testing but generated ex post, based on assumed Poisson’s ratio) are much less hazardous than total disregard of the transverse strain response.
[klicova_slova_en] => Arterial wall mechanics; Constitutive models; Transverse deformation; Poisson's ratio; Model calibration; Hyperfit software
[vysledek_datum] => 2024-02-01T00:00:00+01:00
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[duvernost_udaju_id] => S
[popis] => Zařízení umožnuje s pomocí soustavy senzorů, specializovaných manupulačních prvů a robomotického ramena automatickou montáž a provedení testovacích operací výrobku, který vyžaduje komplexní manipulaci a výrobní operace se zkládají z nelineárních montážních drah.
[popis_orig] => Zařízení umožnuje s pomocí soustavy senzorů, specializovaných manupulačních prvů a robomotického ramena automatickou montáž a provedení testovacích operací výrobku, který vyžaduje komplexní manipulaci a výrobní operace se zkládají z nelineárních montážních drah.
[klicova_slova] => nelineární montá; jemná motorika; robotická manipulace; automatizace
[klicova_slova_orig] => nelineární montá; jemná motorika; robotická manipulace; automatizace
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